With the jump from 2003 Office to 2010 on computers that may have older drivers you may have issues scrolling with the mouse wheel in Excel. This fix needs to be set from the mouse options in control panel, not excel. This issue raised it’s ugly head in Office 2007 – here is the quick fix.
1. Go to CONTROL PANEL -> MOUSE PROPERTIES
2. Then go to the WHEEL TAB – EXCEPTION
3. Then add and browse to the application .exe (In case of excel it is C:\Program Files\Microsoft Office\Office14\Excel.exe)
4. Click APPLY then OK,